Triamcinolone-induced wasting disease in young mice
作者:
M. Silbermann,
T. Kedar,
P. Kovat,
期刊:
Cells Tissues Organs
(Karger Available online 1977)
卷期:
Volume 97,
issue 2
页码: 180-190
ISSN:1422-6405
年代: 1977
DOI:10.1159/000144732
出版商: S. Karger AG
关键词: Triamcinolone;Wasting disease;Mice;Weight;Death
数据来源: Karger
摘要:
Young mice were treated for up to 8 weeks with daily graded doses of triamcinolone diacetate. The body weights of treated, placebo and nontreated animals were measured daily throughout the experimental period, calculated and analysed. By the first injections, significant decrease was noted in the body weight of all experimental mice regardless on their sex or initial body weight. The latter was followed by a so-called ‘steady state’ which longed for approximately 4 weeks. Marked deterioration and mortality also occurred but became severe from the fifth week of triamcinolone administration. Possible explanations for the above findings are discus
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