The excitation intensity and temperature dependences of the photoluminescence (PL) from Ga0.52In0.48P grown by organometallic vapor phase epitaxy on GaAs substrates have been investigated as a function of the epilayer growth temperature and the substrate misorientation from (100). The energy band gap is dependent on substrate temperature during growth but is effectively independent of substrate misorientation. A strong excitation intensity dependence of the PL is found to be a function of both substrate orientation and growth temperature. We postulate that the strong dependence of PL emission energy on excitation intensity in some samples may result from the sizes, shapes, and orientations of ordered domains.