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Liddle Syndrome: Clinical and Cellular Abnormalities

 

作者: WarnockDavid G.,   BubienJames K.,  

 

期刊: Hospital Practice  (Taylor Available online 1994)
卷期: Volume 29, issue 7  

页码: 95-105

 

ISSN:2154-8331

 

年代: 1994

 

DOI:10.1080/21548331.1994.11443050

 

出版商: Taylor&Francis

 

数据来源: Taylor

 

摘要:

Clinical findings resemble those of primary hyperaldosteronism, except that aldosterone secretion is negligible. The fault appears to lie with continuously avid sodium channels in the distal nephron, resulting in excessive salt absorption, potassium wasting, and severe hypertension. Insights gained in this disorder may help clarify more common forms of low-renin hypertension.

 

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