Effects of Carotenoid Administration on Bladder Cancer Prevention
作者:
Micheline M. Mathews-Roth,
Nels Lausen,
Gisele Drouin,
Arnold Richter,
Norman I. Krinsky,
期刊:
Oncology
(Karger Available online 1991)
卷期:
Volume 48,
issue 3
页码: 177-179
ISSN:0030-2414
年代: 1991
DOI:10.1159/000226922
出版商: S. Karger AG
关键词: P-Carotene;Canthaxanthin;Bladder cancer prevention
数据来源: Karger
摘要:
Bladder cancer was induced in male B6D2F1 strain mice by the administration of N-butyl-N-(4-hydroxybutyl)nitrosamine. Mice supplemented with β-carotene for 5 weeks before receiving the carcinogen and maintained on β-carotene for an additional 26 weeks developed significantly fewer tumors than did unsupplemented mice. Mice receiving canthaxanthin for the same time period showed no protection against the development of bladder cancer. effect of this molecule must be an intrinsic property of carotenoid
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