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One-week treatment of tinea corporis and tinea cruris with terbinafine (Lamisil) 1% cream: a placebo-controlled study

 

作者: EvansEGV,   ShahJM,   JoshipuraRC,  

 

期刊: Journal of Dermatological Treatment  (Taylor Available online 1992)
卷期: Volume 3, issue 4  

页码: 181-184

 

ISSN:0954-6634

 

年代: 1992

 

DOI:10.3109/09546639209088719

 

出版商: Taylor&Francis

 

数据来源: Taylor

 

摘要:

In a multicentre double-blind randomized parallel-group study, 31 patients who had mycologically proven tinea corporis or tinea cruris were treated topically with either terbinafine 1% cream or its vehicle, applied once daily for 1 week. The percentage of patients 'effectively treated' (combined mycological and clinical outcome) was 86% for terbinafine compared with 35% for placebo (P = 0.01, Fisher's Exact test, two tailed). No adverse events were reported during the study. Topical terbinafine 1% cream used once daily for 1 week is an effective and well-tolerated treatment for tinea corporis and tinea cruris.

 

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