1-Hydroxypyrene Levels In Coal-Handling Workers at a Coke Oven
作者:
Robert Malkin,
Max Kiefer,
William Tolos,
期刊:
Journal of Occupational and Environmental Medicine
(OVID Available online 1996)
卷期:
Volume 38,
issue 11
页码: 1141-1144
ISSN:1076-2752
年代: 1996
出版商: OVID
数据来源: OVID
摘要:
An environmental and medical survey was conducted at the coal-handling area of a coke oven, where workers came in contact with coal-tar sludge. The purpose of the study was to determine if skin contact with coal-tar sludge was an important route of exposure to pyrene because workers were observed to have substantial contact with the sludge. Environmental monitoring revealed minimal airborne exposure to pyrene, a byproduct of the coke distillation process; only one personal breathing zone sample detected pyrene, and at a level of 0.001 mg/m3. However, the mean preshift urinary 1-hydroxypyrene concentration was 1.00 µmol/mol creatinine (range, 0.16 to 2.96 µmol/mol creatinine) and the mean postshift level was 1.7 µmol/mol creatinine (range, 0.24 to 4.85 µmol/mol creatinine) (P< 0.01). These levels probably reflect absorption as a result of skin exposure.
返 回