Genetic and phenotypic consequences of inbreeding
作者:
WilliamG. Hill,
期刊:
Journal of Toxicology and Environmental Health
(Taylor Available online 1979)
卷期:
Volume 5,
issue 1
页码: 27-42
ISSN:0098-4108
年代: 1979
DOI:10.1080/15287397909529722
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
The effects of inbreeding on heterozygosity, mean performance, variation within and between lines, and fixation or loss of genes are discussed. Theoretical predictions for degree of pedigree inbreeding and consequences for genes neutral with respect to fitness are outlined first, and then the likely modifications necessary to account for natural selection during inbred line development are considered. For illustration, some results from experiments with laboratory animals are reviewed.
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