Diagnostic Aspects and Follow-Up of 174 Cases of Hepatocellular Carcinoma
作者:
L. Buscarini,
F. Fornari,
R. Canaletti,
G. Sbolli,
G. Civardi,
L. Cavanna,
M. Di Stasi,
期刊:
Oncology
(Karger Available online 1991)
卷期:
Volume 48,
issue 1
页码: 26-30
ISSN:0030-2414
年代: 1991
DOI:10.1159/000226889
出版商: S. Karger AG
关键词: Hepatocellular carcinoma, Italy North;Risk factor;Ultrasonically guided fine-needle biopsy;Laparoscopy
数据来源: Karger
摘要:
From June 1981 to June 1989 we diagnosed 174 cases of hepatocellular carcinoma (HCC) at our institution (Piacenza, Northern Italy). Average age was 65.6 years; male to female ratio 3.4. 149 patients were cirrhotic (85.6%); alcohol abuse was present in 88/169 (52.1%); in 53/145 patients all hepatitis B virus markers were negative. Alpha-fetoprotein showed a low diagnostic sensitivity (values above 500 ng only in 49/169 or 29.0%). We used ultrasound (US) examination with a very high identification rate in all cases; pathological diagnosis was achieved by US guided fine-needle aspiration biopsy in 135 patients; in 13, by laparoscopy-histol-ogy. Metastases were found in 24/169 cases (14.2%); a second malignancy was diagnosed in 13/169 (7.7%): the most common association was HCC-non-Hodgkin lymphoma. Only 14 patients could be referred to surgery, which significantly improved prognosis.
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