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Diagnostic Aspects and Follow-Up of 174 Cases of Hepatocellular Carcinoma

 

作者: L. Buscarini,   F. Fornari,   R. Canaletti,   G. Sbolli,   G. Civardi,   L. Cavanna,   M. Di Stasi,  

 

期刊: Oncology  (Karger Available online 1991)
卷期: Volume 48, issue 1  

页码: 26-30

 

ISSN:0030-2414

 

年代: 1991

 

DOI:10.1159/000226889

 

出版商: S. Karger AG

 

关键词: Hepatocellular carcinoma, Italy North;Risk factor;Ultrasonically guided fine-needle biopsy;Laparoscopy

 

数据来源: Karger

 

摘要:

From June 1981 to June 1989 we diagnosed 174 cases of hepatocellular carcinoma (HCC) at our institution (Piacenza, Northern Italy). Average age was 65.6 years; male to female ratio 3.4. 149 patients were cirrhotic (85.6%); alcohol abuse was present in 88/169 (52.1%); in 53/145 patients all hepatitis B virus markers were negative. Alpha-fetoprotein showed a low diagnostic sensitivity (values above 500 ng only in 49/169 or 29.0%). We used ultrasound (US) examination with a very high identification rate in all cases; pathological diagnosis was achieved by US guided fine-needle aspiration biopsy in 135 patients; in 13, by laparoscopy-histol-ogy. Metastases were found in 24/169 cases (14.2%); a second malignancy was diagnosed in 13/169 (7.7%): the most common association was HCC-non-Hodgkin lymphoma. Only 14 patients could be referred to surgery, which significantly improved prognosis.

 

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