Permissive hypercapnia

 

作者: Luca Bigatello,   Nicoló Patroniti,   Fabio Sangalli,  

 

期刊: Current Opinion in Critical Care  (OVID Available online 2001)
卷期: Volume 7, issue 1  

页码: 34-40

 

ISSN:1070-5295

 

年代: 2001

 

出版商: OVID

 

数据来源: OVID

 

摘要:

The termpermissive hypercapniadefines a ventilatory strategy for acute respiratory failure in which the lungs are ventilated with a low inspiratory volume and pressure. The aim of permissive hypercapnia is to minimize lung damage during mechanical ventilation; its limitation is the resulting hypoventilation and carbon dioxide (CO2) retention. In this article we discuss the rationale, physiologic implications, and implementation of permissive hypercapnia. We then review recent clinical studies that tested the effect of various approaches to permissive hypercapnia on the outcome of patients with acute respiratory failure.

 

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