Background: Data regarding radiation treatment of patients with pelvic neoplasms who also have inflammatory bowel disease are limited. Therefore, the effect of pelvic radiation therapy on bowel complications in patients with Crohn's disease is not clearly known.Case Report and Discussion: We describe a patient with stage IB2cervical cancer and Crohn's disease whose planned radical hysterectomy was aborted because of grossly positive pelvic lymph nodes. Therapy consisted of external beam radiation and brachytherapy. Seven months after completion of her radiotherapy, she was diagnosed with a pelvic mass that caused a large bowel obstruction. She underwent computed tomography-guided drainage of the pelvic mass followed by exploratory laparotomy and transverse loop colostomy. The pelvic mass was a concealed abscess. The patient continues to be cancer free 18 months after completion of therapy.Conclusion: Surgical management of cervical cancer should be the preferred treatment in women with Crohn's disease.