Effects of Respiratory Gases on the Frequency and Duration of Obstructive Apneic Episodes in a Patient with the Sleep Apnea-Hypersomnolence Syndrome
作者:
Samuel Kuna,
Joseph Gillen,
Sanford Levine,
期刊:
Respiration
(Karger Available online 1982)
卷期:
Volume 43,
issue 2
页码: 108-113
ISSN:0025-7931
年代: 1982
DOI:10.1159/000194473
出版商: S. Karger AG
关键词: Sleep apnea-hypersomnolence syndrome;Obstructive apneic episodes;Ventilatory control;Hyperoxia;Hypercapnia
数据来源: Karger
摘要:
We studied the effects of hyperoxia and hypercapnia on obstructive apneic episodes (OAE) in a 39-year-old male with the sleep apnea and hypersomnolence syndrome (SAHS). While inspiring room air, our patient spent approximately 50% of his non-REM sleep time in OAE. When the inspired gas was changed to 100% oxygen, the frequency of the OAE decreased slightly, but a statistically significant increase in the duration of each episode was noted. Additionally, a CO2 rebreathe under hyperoxic conditions was carried out during non-REM sleep; no OAE were noted during this rebreathe. Therefore, this latter observation suggests that hypercapnia under hyperoxic conditions may reduce the frequency of OAE in patients with the SAHS.
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