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Effects of Excess NaCl Intake on Blood Pressure and Cholesterol‐Induced Atherosclerosis in the Monkey

 

作者: MOTOOMI NAKAMURA,   HIROAKI MURAKAMI,   UMPEI SHIGEMI,  

 

期刊: Stroke  (OVID Available online 1975)
卷期: Volume 6, issue 1  

页码: 9-16

 

ISSN:0039-2499

 

年代: 1975

 

出版商: OVID

 

关键词: cerebral arteries;xanthomatosis;Macaca irus(monkey);predilection site

 

数据来源: OVID

 

摘要:

TheMacaca irusis a monkey species that is highly susceptible to experimental cholesterol atherosclerosis of the aorta, coronary and cerebral arteries and cutaneous xanthomatosis-like lesions induced by feeding a diet high in cholesterol and/or coconut oil for 14 months.The monkeys fed an atherogenic diet were divided into two groups: monkeys receiving excess sodium and controls. The excess sodium group showed a significantly higher systolic blood pressure as compared with the control group; however, elevation of blood pressure was mild and was not considered as significant hypertension.The loading of excess sodium chloride in monkeys fed an atherogenic diet did not enhance severity of atherosclerosis of the aorta, coronary and cerebral arteries.

 

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