Studies of the Labelling of Human Serum Albumin with99mTc Using Sn(II) Tartrate and Sn(II)Cl2as Reducing Agents
作者:
M. T. El-Kolaly,
H. A. El-Asrag,
A. S. El-Wetery,
A. A. El-Mohty,
期刊:
Isotopenpraxis Isotopes in Environmental and Health Studies
(Taylor Available online 1990)
卷期:
Volume 26,
issue 2
页码: 64-68
ISSN:0021-1915
年代: 1990
DOI:10.1080/10256019008624228
出版商: Taylor & Francis Group
关键词: albumins;ascorbic acid;blood serum;labelling;reducing agents;technetium 99m;tin chlorides;tissue distribution
数据来源: Taylor
摘要:
A comparative study has been carried out on the effect of Sn(II) tartrate and Sn(II)Cl2on the labelling efficiency and tissue distribution of99mTc-human serum albumin. The effect of reductant content, reaction time (incubation time), albumin content, pH, and ascorbic acid on the efficiency of labelling and the tissue distribution of the labelled albumin has been investigated. The percent labelling was determined by paper and thin layer radiochromatography. Ascorbic acid shows no effect on either labelling efficiency or tissue distribution of99mTc-HSA prepared by Sn(II) tartrate or Sn(II)Cl2.
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