Comparative Evaluation of Technetium‐99m Glucoheptonate and Gallium‐67 Citrate Thoracic Imaging in Detection of Mediastinal and Hilar Involvement in Primary Lung Cancer
作者:
RAYMOND TAILLEFER,
GILLES BEAUCHAMP,
JEAN LÉVEILLÉ,
期刊:
Clinical Nuclear Medicine
(OVID Available online 1986)
卷期:
Volume 11,
issue 1
页码: 15-19
ISSN:0363-9762
年代: 1986
出版商: OVID
数据来源: OVID
摘要:
Fifty-two patients with proven primary lung cancer who were referred for mediastinoscopy were prospectively studied with Tc-99m glucoheptonate and Ga-67 citrate thoracic scintigraphy. Primary lung tumors concentrated Ga-67 in 92% of cases, compared to 88% for Tc-99m glucoheptonate. Mediastinoscopy confirmed the presence of mediastinal metastases in 23 patients. The sensitivity of Tc-99m glucoheptonate and Ga-67 scans for mediastinal involvement detection is respectively 52% and 83%, for a specificity of 100% (Tc-99m glucoheptonate) and 88% (Ga-67). Twenty-nine patients underwent thoracotomy after a negative mediastinoscopy. Hilar metastatic involvement was present in eight patients. The sensitivity and the specificity for detection of hilar involvement were respectively 63% and 95% for Tc-99m glucoheptonate and 88% and 78% for Ga-67. Although more specific than Ga-67 scan, Tc-99m glucoheptonate thoracic imaging cannot be recommended in the staging of lung cancer because of its low sensitivity in the detection of intrathoracic metastatic spread of primary lung carcinoma.
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