Recent studies of ribonuclease P
作者:
Sidney Altman,
Leif Kirsebom,
Simon Talbot,
期刊:
The FASEB Journal
(WILEY Available online 1993)
卷期:
Volume 7,
issue 1
页码: 7-14
ISSN:0892-6638
年代: 1993
DOI:10.1096/fasebj.7.1.7916700
出版商: Wiley
数据来源: WILEY
摘要:
RNase P is an essential enzyme that is required for the biosynthesis of tRNA. It is composed of RNA and protein subunits. The RNA subunit of the enzyme derived from eubacterial sources can carry out the catalytic function by itself in vitro. Current studies of RNase P focus on structure‐function relationships with respect to interactions of the RNA subunit with its substrates and with respect to the determination of the kinetic parameters of the reaction, the role of the protein component, and the rules governing recognition of substrates.— Altman, S.; Kirsebom, L., Talbot, S. Recent studies of ribonuclease P.FASEB J.7: 7‐14; 1993.
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