Trials that pertain to angioplasty and restenosis are a major focus of clinical research in cardiology at present. Investigators, especially those involved in multicenter studies, have become experts in the derivation of acronyms to identify these trials. Meant to capture the spirit of the trial and the attention of those reading the eventual publication of the results, these abbreviations have proliferated in recent times. This article summarizes the major trials with acronym titles, spells out what they stand for, defines what was investigated, and reviews the reported results. (J Interven Cardiol 1992; 5:29–3