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Technique of Experimental Aneurysm Formation in the Rat Common Carotid Artery Using the Milliwatt Carbon Dioxide Laser and the Adventitia Patch Model

 

作者: Mario Ammirati,   Jeffrey Cozzens,   Theodore Eller,   Ivan Ciric,   Joseph Tarkington,   Eleanor Rabin,  

 

期刊: Neurosurgery  （OVID Available online 1986）
卷期: Volume 19, issue 5  

页码: 732-734

 

ISSN:0148-396X

 

年代: 1986

 

出版商: OVID

 

关键词: Carbon dioxide laser;Common carotid artery;Experimental aneurysm;Rat;Subarachnoid hemorrhage

 

数据来源: OVID

 

摘要:

&NA;Aneurysms were induced in the rat common carotid artery by using the milliwatt cardon dioxide laser to weld an adventitia patch over a hole. This technique proved to be effective and reliable as demonstrated by the 100% incidence of aneurysm formation at the patch site in 28 rats killed 1 week or later after the procedure. It is suggested that this technique may be used to produce intracranial aneurysms in experimental animals due to the minimal vessel manipulation required. (Neurosurgery19:732‐734, 1986)

 

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