Never Ending Growth and a Growth Factor. I. Immunocytochemical Evidence for the Presence of Basic Fibroblast Growth Factor in a Tapeworm
作者:
GustafssonMargaretha K. S.,
ErikssonKrister,
期刊:
Growth Factors
(Taylor Available online 1992)
卷期:
Volume 7,
issue 4
页码: 327-334
ISSN:0897-7194
年代: 1992
DOI:10.3109/08977199209046415
出版商: Taylor&Francis
关键词: bFGF;nerve cells;tapeworm;immunocytochemistry;Western blot
数据来源: Taylor
摘要:
AbstractBasic fibroblast growth factor immunoreactivity (bFGF-IR) was detected in a specific set of nerve cells in the central nervous system of the gull-tapewormDiphyllobothrium dendriticum(Cestoda)—an obligatory endoparasite. The long varicose processes of the bFGF-IR neurons extend along the two main nerve cords, which contain an actively growing population of nerve cells. A neurotrophic function for the bFGF-like material is proposed. The adult tapeworm lives in the intestine of a homeothermic host and has a pattern of very active and never ending growth. The larval stages live in poikilothermic hosts and grow very slowly. The bFGF-IR nerve cells occur both in II stage larvae and in adult worms. Thus, no correlation between the presence of bFGF-IR and the general growth rate of the worm was found. Western blot analysis revealed the presence of an anti-bFGF immunoreactive peptide with a molecular mass of 47 kDa in both larval and adult worms.
点击下载:
PDF (3087KB)
返 回