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Retention Time and the First Time Moment in Elution Chromatography. I. The Column Characteristic Ĝ

 

作者: JamesE. Funk,   PeterR. Rony,  

 

期刊: Separation Science  (Taylor Available online 1971)
卷期: Volume 6, issue 3  

页码: 365-381

 

ISSN:0037-2366

 

年代: 1971

 

DOI:10.1080/00372367108055562

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

A useful chromatographic parameter–the column characteristic, [Ggrave]–is defined and derived. It contains all of the dynamic information of interest for chromatography, yet it can be determined from a single-stage experiment. The column characteristic can be employed directly to derive the column transfer function and is related to the Murphree stage efficiency for the chromatographic column operated as a single equilibrium stage. The relationship of the column characteristic to the first normal statistical moment is derived. Application is made to a simple physical situation and results are obtained for both a distributed and a discrete description of the stationary liquid phase. The nature of the discrete approximation is discussed. This paper provides the foundation for two additional papers that explore in detail several aspects of nonequilibrium chromatography.

 

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