Human chromogranin A‐like immunoreactivity in the bergmann glia of the rat brain
作者:
W. Geoffrey McAuliffe,
Arthur Hess,
期刊:
Glia
(WILEY Available online 1990)
卷期:
Volume 3,
issue 1
页码: 13-16
ISSN:0894-1491
年代: 1990
DOI:10.1002/glia.440030103
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: Chromogranin A;Golgi epithelial cells;Cerebellum
数据来源: WILEY
摘要:
AbstractA mouse monoclonal antibody to human chromogranin A (LK2H10) selectively stains the Bergmann glia (Golgi epithelial cells) of the rat cerebellum, while rabbit antibodies to bovine or porcine chromogranin A do not. Chromogranin A immunostaining in the cell bodies and processes reveals the characteristic candelabra morphology seen in Golgi preparations of these cells. Immunostaining adjacent sections with antibodies to glial fibrillary acidic protein shows that a relatively small number of the glial cell processes in the molecular layer are chromogranin A positive. Recent reports indicate that the metabolites of chromogranin A play a regulatory role in endocrine and neuroendocrine systems but the function of chromogranins in neurons and glia is unknown.
点击下载:
PDF
(463KB)
返 回