Total mercury concentrations were measured in the muscle of different kinds of fish: megrim (Lepidorhombus boscii), common sole (Solea vulgaris), striped mullet (Mullus barbatus), anglerfish (Lophius piscatorius), and black-bellied angler (Lophius budegassa), caught in the South Adriatic Sea (South Italy). The highest total mercury levels were found in anglerfish (0.61-2.22 mg/kg wet wt, mean 1:26±0.58), followed by black-bellied angler (0.22±1.62 mg/kg wet wt, 0.68±0.36), megrim (0.05±0.92 mg/kg wet wt, 0.39±0.30), striped mullet (0.10±0.63 mg/kg wet wt, 0.31±0.13) and common sole (0.05±0.44 mg/kg wet wt, 0.19 ±0.15). According to current regulations, 62.5% of anglerfish (Lophius piscatorius) and 23% of black-bellied angler (Lophius budegassa) samples showed concentrations exceeding the peak value of 1 mg/kg, while only 25% of samples of megrim (Lepidorhombus boscii), and 8.3% of striped mullet (Mullus barbatus), exceeded the peak value fixed at 0.5mg/kg. Correlations between total mercury concentration and specimen weight were evident in all the species examined.