HIV‐2 infection in an American
作者:
Thomas O'Brien,
Charlene Polon,
Charles Schable,
Nancy VanDevanter,
Mark Rayfield,
David Wallace,
Ann Stuart,
Scott Holmberg,
期刊:
AIDS
(OVID Available online 1991)
卷期:
Volume 5,
issue 1
页码: 85-88
ISSN:0269-9370
年代: 1991
出版商: OVID
关键词: HIV-2;AIDS;surveillance;United States;epidemiology
数据来源: OVID
摘要:
HIV-2 is endemic in West Africa but rare elsewhere. In the USA there have been 18 reported cases of HIV-2 infection; most identified people have been West Africans. We recently diagnosed the first case of HIV-2 infection in a native-born US citizen, a woman whose serum was found to be reactive to anti-HIV-1 enzyme immunoassay (EIA) when she attempted to donate blood in 1986. Although both HIV-1− and HIV-2-specific EIAs were reactive, the anti-HIV-2 Western blot (WB) was positive, while the anti-HIV-1 WB was positive or indeterminate on different occasions. Synthetic peptide testing was reactive for HIV-2 but not HIV-1. HIV-2 DNA was detected using the polymerase chain reaction procedure. Although she had travelled to West Africa, it is unclear how she became infected with HIV-2.
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