Unrecognized Pseudohyperkalemia as a Cause of Elevated Potassium in Patients with Renal Disease
作者:
Onyekachi Ifudu,
Mariana S. Markell,
Eli A. Friedman,
期刊:
American Journal of Nephrology
(Karger Available online 1992)
卷期:
Volume 12,
issue 1-2
页码: 102-104
ISSN:0250-8095
年代: 1992
DOI:10.1159/000168425
出版商: S. Karger AG
关键词: Pseudohyperkalemia;Hemodialysis;Thrombocytosis
数据来源: Karger
摘要:
Pseudohyperkalemia, defined as serum to plasma potassium difference of more than 0.4 mmol/l, occurs when platelets, leukocytes or erythrocytes release intracellular potassium in vitro, leading to falsely elevated serum values. Pseudohyperkalemia has been observed in myeloproliferative disorders [ 1 ], including leukemia [2] and infectious mononucleosis [3] as well as in rheumatoid arthritis [4]. We present 2 patients with renal disease and thrombocytosis in whom pseudohyperkalemia was recognized only after common therapeutic measures and/or dialysis failed to effect a decrease in serum potassium. In patients with renal disease and thrombocytosis, plasma as well as serum potassium should be routinely measured prior to instituting aggressive therapy or altering dialysis prescription in order to avoid potentially dangerous overtreatment with resulting hypokalemia.
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