Since Sideman et al.[1]derived an analytical solution of the Nusselt number for a spherical drop in the direct contact evaporation in an immiscible liquid, many researchers have performed theoretical research on this field under different assumptions [2]-[6]. However drops moving in another immiscible liquid do not take a spherical form, but oblate form, which may be well approximated as an ellipsoid. This paper establishes the mathematical model of heat transfer for a moving ellipsoidal drop in an immiscible liquid, and presents results from numerical calculation. The relationship of the Nusselt number with the Weber number and the Peclet number is given, which is suitable for a relatively large range ofWeandPe. The theoretical results for the Nusselt number show good agreement with experimental data. Some important conclusions are obtained.