Enzyme Immunoassay for Detection ofNeisseria gonorrhoeaeFrom Urogenital Samples
作者:
LOUIS GRUBIN,
NEWTON OSBORNE,
期刊:
Obstetrics & Gynecology
(OVID Available online 1987)
卷期:
Volume 69,
issue 3
页码: 350-353
ISSN:0029-7844
年代: 1987
出版商: OVID
数据来源: OVID
摘要:
A solid-phase enzyme immunoassay (Gonozyme) was used to detectNeisseria gonorrhoeae; the results were compared with the results of cultures taken simultaneously from 201 patients from sexually transmitted disease clinics or family planning clinics. Cultures were positive in 32 of 201 consecutive patients seen in the clinics, while the Gonozyme was positive in 28 of these patients. Overall, five positive cultures were not detected by the Gonozyme, and one positive Gonozyme was not confirmed by culture in the 201 patients tested. The overall sensitivity of the enzyme immunoassay was 84.4% and the specificity 99.4%. The predictive values of a positive and negative Gonozyme result were 96.4 and 97.1%, respectively.
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