Uneventful total intravenous anaesthesia with ketamine for schizophrenic surgical patients
作者:
H. Ishihara,
H. Kudo,
T. Murakawa,
A. Kudo,
S. Takahashi,
A. Matsuki,
期刊:
European Journal of Anaesthesiology
(OVID Available online 1997)
卷期:
Volume 14,
issue 1
页码: 47-51
ISSN:0265-0215
年代: 1997
出版商: OVID
关键词: Schizophrenia;Anaesthetic Agents;Ketamine;Total Intravenous Anaesthesia
数据来源: OVID
摘要:
Ketamine has been considered to be contraindicated for schizophrenic patients because it may induce psychologial emergence reactions and psychiatric deterioration. Total intravenous anaesthesia (TIVA) with ketamine combined with droperidol and fentanyl (DFK) has been used in 14 schizophrenic patients undergoing various surgical procedures. Two patients died post-operatively of concomitant severe disease rather than from schizophrenia related pathophysiology or anaesthetic complication. One patient showed transient mild anxiety in the early post-operative period soon relieved by the patient's routine medication. However, no patient developed exacerbations of psychosis or psychological emergence reactions during the first post-operative month. The cardiovascular state during and after DFK remained stable in all cases. It is concluded that ketamine when combined with droperidol and fentanyl is a satisfactory anaesthetic for patients with schizophrenia.
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