Primary and metastatic carcinomas in the digits of cats
作者:
J.S. van der Linde‐Sipman,
Th.S.G.A.M. van den Ingh,
期刊:
Veterinary Quarterly
(Taylor Available online 2000)
卷期:
Volume 22,
issue 3
页码: 141-145
ISSN:0165-2176
年代: 2000
DOI:10.1080/01652176.2000.9695043
出版商: Taylor & Francis Group
关键词: Carcinoma;cats;digits;immunohistochemistry;metastatic;primary
数据来源: Taylor
摘要:
In the period 1993–1998, digital carcinomas in 64 cats were examined. In all animals primary complaints were painful digit(s). Eight cats had a primary squamous cell carcinoma which involved one digit or two adjacent digits of one leg. Fifty‐six cats had metastases of a pulmonary carcinoma in the digits, and in general multiple digits of different legs were involved. In many of these cats metastases also occurred in other organs, including the skin and muscles. No primary sweat gland carcinomas of the digits were seen. Primary squamous cell carcinomas of the digits were characterized by cornification and the absence of PAS‐positive cells, PAS‐positive secretory material. Immunohistochemically, these neoplasms stained negative with the monoclonal antibody CAM 5.2 directed against Keratin 8 (K 8). The metastases of pulmonary carcinomas to the digits showed one or more of the following histological features: goblet cells, ciliated epithelial cells, PAS‐positive cells or lakes, and/or a PAS‐positive lining of luminal membranes and no cornification. Immunohistochemically, they showed positive staining for CAM 5.2 (K8).
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