Spectral shift of fluorescein and carboxyfluorescein in the anterior chamber of the rabbit eye following systemic administration
作者:
NeaultThomas R.,
McLarenJay W.,
BrubakerJill H.,
BrubakerRichard F.,
期刊:
Current Eye Research
(Taylor Available online 1986)
卷期:
Volume 5,
issue 5
页码: 337-341
ISSN:0271-3683
年代: 1986
DOI:10.3109/02713688609025171
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Systemically administered fluorescein is converted to fluorescein glucuronide. The conjugate is fluorescent and interferes with the measurement of fluorescein in the anterior chamber. Carboxyfluorescein is a hydrophilic derivative of fluorescein. In the rabbit, carboxyfluorescein is not converted as readily to a fluorescent metabolite. Thus, carboxyfluorescein has potential advantages as a quantitative fluorophore for studies of aqueous humor dynamics.
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