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Gene dose effect: intraband mapping of theLDH Alocus using cells from four individuals with different interstitial deletions of 11p

 

作者: U. Francke,   D.L. George,   M.G. Brown,   V.M. Riccardi,  

 

期刊: Cytogenetic and Genome Research  （Karger Available online 1977）
卷期: Volume 19, issue 4  

页码: 197-207

 

ISSN:1424-8581

 

年代: 1977

 

DOI:10.1159/000130809

 

出版商: S. Karger AG

 

数据来源: Karger

 

摘要:

The quantitative expression of LDH A was studied in hemolysates from four patients with different but overlapping interstitial deletions of the short arm of chromosome 11. Deficiency of LDH A was demonstrated in one patient, and the LDH A locus has been assigned to that segment of lip for which this patient alone was deficient, i.e., to band llpl2 (region 11p1203→11p1208

 

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