Absence of Serum‐Stimulated Lipase Activity and Altered Lipid Content in Milk from a Patient with Type I Hyperlipoproteinaemia
作者:
G. BERGER,
A. SPARK,
P. BAILLIE,
J. HUSKISSON,
G. STOCKWELL,
E. DER MERWE,
期刊:
Pediatric Research
(OVID Available online 1983)
卷期:
Volume 17,
issue 10
页码: 835-838
ISSN:0031-3998
年代: 1983
出版商: OVID
数据来源: OVID
摘要:
We measured the serum-stimulated lipase activity, fatty acid content, and various biochemical parameters in the breast milk of a lactating mother suffering from familial lipoprotein lipase deficiency and of healthy control subjects. Serum-stimulated lipase activity was virtually undetectable in milk from our patient and the total fatty acid content was low. The fatty acid composition differed from normal showing a marked absolute and relative increase in the content of lauric (C12:0) and myristic (C14:0) fatty acids and considerably reduced levels of oleic (C18:1) and especially linoleic (C18:2) acids. Other fatty acid species showed lesser changes in concentration. Besides a reduced calcium concentration in the milk from our patient, other biochemical parameters were not significantly different from control subjects.
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