Restriction fragment length polymorphism of the caprine ß‐globin gene cluster associated with the Hb ß‐globin variants in Norwegian dairy goats
作者:
O. BERGERSEN,
M. BRAEND,
期刊:
Animal Genetics
(WILEY Available online 1991)
卷期:
Volume 22,
issue 1
页码: 53-65
ISSN:0268-9146
年代: 1991
DOI:10.1111/j.1365-2052.1991.tb00646.x
出版商: Blackwell Publishing Ltd
关键词: Keywords:;goat haemoglobin;RFLP;ß‐globin genes;linkage disequilibrium
数据来源: WILEY
摘要:
Summary.Restriction fragment length polymorphism (RFLP) analysis was used to characterize the ß‐globin cluster in Norwegian dairy goats. In 122 individuals, different RFLP patterns were detected after BglII andPstI digestion and hybridization with acaprineß‐globin probe. The location of the polymorphicBglII andPstI sites were determined. The different RFLPs were in linkage disequilibrium with each other and with the ß‐globin locus as studied at the protein level. A preferential association between certain RFLP haplotypes and ß‐globin variants was observed.Polymorphic DNA fragments in the e‐globin genes were detected afterMspI digestion and hybridization with acaprinee‐probe, and eight different band patterns were observed. Correlation between differentMspI haplotypes and the ß‐globin varia
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