Idiopathic Thrombocytopenic Purpura Presenting as Iron-Responsive Thrombocytopenia
作者:
Joseph Michaeli,
Dan Admon,
Gilles Lugassy,
Yaacov Matzner,
期刊:
Pathophysiology of Haemostasis and Thrombosis
(Karger Available online 1987)
卷期:
Volume 17,
issue 1-2
页码: 105-108
ISSN:1424-8832
年代: 1987
DOI:10.1159/000215565
出版商: S. Karger AG
关键词: Idiopathic thrombocytopenic purpura;Iron responsive thrombocytopenia;Iron and thrombopoiesis
数据来源: Karger
摘要:
We describe a patient with iron-deficiency anemia, thrombocytopenia and paucity of marrow megakaryocytes, in whom the anemia and the thrombocytopenia responded to the administration of iron. Thrombocytopenia recurred, despite maintenance of normal hemoglobin and iron levels and adequate marrow megakaryocytes. Corticoste-roids and splenectomy were required for the control of the thrombocytopenia. In this patient, the initial manifestations of idiopathic thrombocytopenic purpura were modified by the presence of severe iron deficiency. This case strengthens the contention that iron is essential for megakaryopoiesis and thrombopoiesis.
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