The effects of irradiation pulsing on the enhanced climb-glide creep strain are analyzed. A variety of pulsed systems have been studied by adytically modeling the time-dependence of the bulk point-defect concentrations given by the rate theory. Equations for the creep strain are derived for Tokamak-type fusion reactors, pulsed accelerators and inertial confinement fusion reactors, including the effects of mutual point-defect recombination. The creep in pulsed fusion reactors is compared with the creep in systems subject to steady irradiation of equal total dose. It is found that point-defect concentration cycling (due to radiation pulsing) results in enhancement of the irradiation creep strain. In particular, a very large temperature-dependent enhancement is found for inertial confinement fusion reactors. The theoretical results are also compared with experimental data on deuteron irradiated nickel. Good agreement is obtained with the parameters used.