Relationship between solubility and hemolytic effects of toxic dusts
作者:
S. V. Singh,
Ballabh Das,
Qamar Rahman,
期刊:
Journal of Applied Toxicology
(WILEY Available online 1983)
卷期:
Volume 3,
issue 1
页码: 14-17
ISSN:0260-437X
年代: 1983
DOI:10.1002/jat.2550030105
出版商: John Wiley&Sons, Ltd.
关键词: toxic dusts;solubility;erythrocytes;membrane lysis;toxicity
数据来源: WILEY
摘要:
AbstractTwo varieties of native and chemically treated slate dust were testedin vitrofor their hemolytic effects and the extent of silicic acid dissolution in various physiological fluids. The extent of hemolysis was found to be proportional to the degree of dissolution of dust constituents. Membrane lysis by the dust appeared to be prevented by coating it with polyvinyl pyrrolidone, serum proteins and pulmonary lavage lipids. The significance of the findings is discussed.
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