Regeneration of axons from central neurons into microchips at the level of the spinal cord
作者:
Göran Lundborg,
Johan Drott,
Lars Wallman,
Martina Reimer,
Martin Kanje,
期刊:
NeuroReport
(OVID Available online 1998)
卷期:
Volume 9,
issue 5
页码: 861-864
ISSN:0959-4965
年代: 1998
出版商: OVID
关键词: CNS;Microchips;Nerve grafting;Nerve regeneration;Nerve repair;Silicone tubes
数据来源: OVID
摘要:
AXONS from central neurons can regenerate into the tissue matrix formed within a silicone tube capped with two pieces of peripheral nerve, one of which had been sutured to a lesion in the spinal cord. Such axons can grow through a transversely positioned microchip in the tube. These observations suggest that it is feasible to establish functional contact between external electronic equipment and regenerating central nervous axons making it possible to monitor and control their electrical activity. The findings open new perspectives for restoration of motor and sensory functions following spinal cord lesions.
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