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Teratological effects of Western equine encephalitis virus on the fetal nervous system ofMacaca mulatta

 

作者: W. T. London,   N. H. Levitt,   G. Altshuler,   B. L. Curfman,   S. G. Kent,   A. E. Palmer,   J. L. Sever,   S. A. Houff,  

 

期刊: Teratology  （WILEY Available online 1982）
卷期: Volume 25, issue 1  

页码: 71-79

 

ISSN:0040-3709

 

年代: 1982

 

DOI:10.1002/tera.1420250110

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

数据来源: WILEY

 

摘要:

AbstractFetal rhesus monkeys were inoculated intracerebrally with an attenuated strain of western equine encephalitis virus. All animals developed micrencephaly. Twelve of sixteen monkeys developed ex vacuo hydrocephalus. All virus inoculated fetuses developed WEE virus antibody. Virus could hot be recovered at the time of delivery. Monkeys with the highest WEE antibody titers showed the greatest degree of hydrocephalus.

 

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