Decreased Renal Phosphate Threshold in Patients with Gout
作者:
Y. Nishida,
K. Ito,
期刊:
Nephron
(Karger Available online 1992)
卷期:
Volume 62,
issue 2
页码: 142-144
ISSN:1660-8151
年代: 1992
DOI:10.1159/000187022
出版商: S. Karger AG
关键词: Gout;Hypophosphatemia;Renal phosphate threshold
数据来源: Karger
摘要:
Serum and 24-hour urinary phosphate levels in primary gout patients and control subjects were measured. About 45% of gouty patients showed mild hypophosphatemia. However, mean 24-hour urinary excretion of phosphate was significantly elevated as compared with that of controls. Gouty patients showed a significantly decreased tubular reabsorption of phosphate and renal phosphate threshold. It seems that tubular phosphate transport in gouty patients is impaired, and this is the major cause of hypophosphatemia.
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