The conformation of the macrocyclic polyoxo-oligo ethers and esters of cation binding ability have been known to play important role due to appropriate orientation of molecular orbitals cousing selective binding on the cationic radii. The oxygen dipoles are enabled to arrange their p orbitals to the direction of delocalised positive charge. The energy transfer -or exchange- between the ion and ligand shell determined the maximum stability and the stoichiometry of the complexation. Accordingly flexibility or the rigidity of the polyoxo-ether-ester ring cousing from the hindered rotation of cyclic lactone mostly determined the degree of association with the cation.