Epidermal Antihyperplastic Effects of Contact Antiphlogistics
作者:
Erich G. Weirich,
Josef K. Longauer,
Alan H. Kirkwood,
期刊:
Dermatology
(Karger Available online 1978)
卷期:
Volume 156,
issue 1
页码: 1-7
ISSN:1018-8665
年代: 1978
DOI:10.1159/000250890
出版商: S. Karger AG
关键词: Antihyperplastic effect;Contact antiphlogistics;Dermatocorticoids
数据来源: Karger
摘要:
The inhibitory effects of six contact antiphlogistics and two dermatocorticoids on hexadecane-induced hyperplasia of the guinea-pig skin were tested and compared. On the basis of the results obtained, the substances can be ranked in the following order of potency (percent inhibition of surface epithelial proliferation): acetylsalicylic acid (7.9%), phenylbutazone (12.5%), bufexamac (16.4%), bendazac (16.6%), oxyphenbutazone (19.5%), indomethacin (20.0%), hydrocortisone (20.6%) and fluocinolone acetonide (32.0%).
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