首页   按分类浏览 期刊浏览 卷期浏览 Synthesis of 5H‐10,11‐dihydropyrazolo[5,1‐c]‐[1,4]benzodiazepinederivatives. II
Synthesis of 5H‐10,11‐dihydropyrazolo[5,1‐c]‐[1,4]benzodiazepinederivatives. II

 

作者: Fabrizio Melani,   Lucia Cecchi,   Guido Filacchioni,  

 

期刊: Journal of Heterocyclic Chemistry  （WILEY Available online 1984）
卷期: Volume 21, issue 3  

页码: 813-815

 

ISSN:0022-152X

 

年代: 1984

 

DOI:10.1002/jhet.5570210335

 

出版商: Wiley‐Blackwell

 

数据来源: WILEY

 

摘要:

AbstractEthyl 3(5)‐formylpyrazole‐5(3)‐carboxylate, 2‐nitrobenzyl bromide or 2‐nitrobenzoyl chloride are the starting basic materials to prepare with a few reaction steps, pyrazolo[5,1‐c][1,4]benzodiazepines bearing at position 2 a substituted propionic chain (7–9) or bearing at position 5 a carbonyl group (12). Compounds7–9, 12are to be considered aza analogs of the antitumor antibi

 

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