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Conformation and ion channel properties of a five‐helix bundle protein

 

作者: Emmanuelle Dé,   Laurent Chaloin,   Annie Heitz,   Jean Méry,   Gérard Molle,   Frédéric Heitz,  

 

期刊: Journal of Peptide Science  （WILEY Available online 2001）
卷期: Volume 7, issue 1  

页码: 41-49

 

ISSN:1075-2617

 

年代: 2001

 

DOI:10.1002/psc.293

 

出版商: John Wiley&Sons, Ltd.

 

关键词: amphipathic peptide;conformation;five‐helix bundle;ion channel

 

数据来源: WILEY

 

摘要:

AbstractThe primary amphipathic peptide Ac‐Met‐Gly‐Leu‐Gly‐Leu‐Trp‐Leu‐Leu‐Val‐Leu10‐Ala‐Ala‐Ala‐Leu‐Gln‐Gly‐Ala‐Lys‐Lys‐Lys20‐Arg‐Lys‐Val‐NH‐CH2‐CH2‐SH called SPM was able to induce formation of ion channels into planar lipid bilayers with main conductance values of 75 and 950 pS in 1

 

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