Localization of chondroitin sulphate and dermatan sulphate in human dental pulps — an immunohistochemical study
作者:
P. M. BARTOLD,
U. SCHLAGENHAUF,
期刊:
International Endodontic Journal
(WILEY Available online 1995)
卷期:
Volume 28,
issue 1
页码: 19-24
ISSN:0143-2885
年代: 1995
DOI:10.1111/j.1365-2591.1995.tb00151.x
出版商: Blackwell Publishing Ltd
关键词: chondroitin sulphate;dermatan sulphate;proteoglycans;pulp
数据来源: WILEY
摘要:
SummaryThe distribution of dermatan sulphate and chondroitin sulphate in human dental pulps has been assessed using monoclonal antibodies and immunoperoxidase localization techniques. The pulpal tissues were reacted with specific antibodies following pretreatment of the sections with chondroitinase ACII or chondroitinase ABC. Both the 4‐ and 6‐sulphated isomers of chondroitin sulphate were detected in the tissues studied. Very little derrmatan sulphate could be detected. These glycosaminoglycans appeared throughout the pulpal connective tissues with a particularly strong localization to the region adjacent to the odontoblastic and predentine layers. Such distribution strongly implicates chondroitin sulphate in the mineralization process of human dent
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