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I(C3b/C4b Inactivator) Typing by Agarose Gel Isoelectric Focusing and Immunoblotting Technique

 

作者: Hiroaki Nishimukai,   Yoshihiro Tamaki,  

 

期刊: Human Heredity  （Karger Available online 1986）
卷期: Volume 36, issue 3  

页码: 195-197

 

ISSN:0001-5652

 

年代: 1986

 

DOI:10.1159/000153624

 

出版商: S. Karger AG

 

关键词: I(C3b/C4b inactivator);Genetic polymorphism;Isoelectric focusing;Immunoblotting

 

数据来源: Karger

 

摘要:

Genetic polymorphism of I(C3b/C4b inactivator) was studied by the method of agarose gel isoelectric focusing followed by an immunoblotting technique. Serum or plasma samples were pretreated with neuraminidase. The method is rapid, and gives the simple and reliable patterns of I. The allele frequencies calculated from healthy Japanese individuals living in the western part of Japan were: IF*A = 0.126 and IF*B = 0.874.

 

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