Peptide Component Vaccine Engineering: Targeting the AIDS Virus
作者:
CeaseKemp B.,
期刊:
International Reviews of Immunology
(Taylor Available online 1990)
卷期:
Volume 7,
issue 1
页码: 85-107
ISSN:0883-0185
年代: 1990
DOI:10.3109/08830189009061767
出版商: Taylor&Francis
关键词: AIDS;vaccines;synthetic peptides;epitopes
数据来源: Taylor
摘要:
Most of the successful vaccines developed to date induce protective immunity resembling that produced by natural infection. HIV infection does not induce protective immunity. Thus, previously successful approaches based on live- or killed-virus preparations may not yield an effective and safe AIDS vaccine and many feel that a more highly engineered vaccine will be required. Synthetic peptides represent extremely powerful tools for vaccine research and construct optimization. The theory and practice of vaccine engineering using synthetic peptide components is reviewed with special emphasis on progress towards development of a vaccine for AIDS.
点击下载:
PDF (1660KB)
返 回