COMPARISON OF TWO METHODS OF PREPARATION OF THE STATIONARY PHASE FOR HPLC CHIRAL COLUMNS BASED ONtris(3,5-DIMETHYLPHENYLCARBAMOYL) CELLULOSE
作者:
Vladimir Vinković,
Luca Stucchi,
Luciano Navarini,
Vitomir Šunjić,
期刊:
Journal of Liquid Chromatography & Related Technologies
(Taylor Available online 1999)
卷期:
Volume 22,
issue 7
页码: 1041-1053
ISSN:1082-6076
年代: 1999
DOI:10.1081/JLC-100101716
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Stationary phase based ontris(3,5-dimethylphenylcarbamoyl) cellulose is prepared under various conditions (precipitation, evaporation, sieving), and examined in HPLC columns for enantioseparation of racemic mixtures 1–10. Number of theoretical plates (N) and separation parameters (α and RS) are compared with those obtained with commercially available column based on the same polymeric material (Chiralcel OD, from Daicel Co.). Higher efficiency of the columns prepared by precipitation under specific conditions and followed by sieving of stationary phase, over those prepared by evaporation and (or without) sieving, is demonstrated.
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