MYASTHENIA GRAVIS WITH THYMOMA IS NOT ASSOCIATED WITH AN INCREASED INCIDENCE OF NON-MUSCLE AUTOIMMUNE DISORDERS
作者:
AarliJohan A.,
GilhusNils E.,
MatreRoald,
期刊:
Autoimmunity
(Taylor Available online 1992)
卷期:
Volume 11,
issue 3
页码: 159-162
ISSN:0891-6934
年代: 1992
DOI:10.3109/08916939209035150
出版商: Taylor&Francis
关键词: Autoantibodies;autoimmune diseases;autoimmunity;myasthenia gravis;thymoma, thymus
数据来源: Taylor
摘要:
Three groups of thymectomized patients with myasthenia gravis (MG) were selected for study, 16 with thymoma, 16 with thymic atrophy and 32 with follicular hyperplasia of the thymus. All 16 patients with thymoma, 15/16 with thymus atrophy and 30/32 with follicular hyperplasia had AChR antibodies. Non-receptor muscle (CA) antibodies were found in sera of 15/16 patients with thymoma, 3/16 with thymus atrophy and in none of the sera from patients with follicular hyperplasia. There were 2 patients with thymoma and polymyositis, but none of the thymoma patients had rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) or other autoimmune disorders. Among the 32 patients with follicular hyperplasia of the thymus were 2 with SLE, 2 with RA and 1 with juvenile diabetes mellitus.In this study, there was an increased incidence of non-muscle autoimmune disorders among MG patients with follicular hyperplasia of the thymus but not among MG patients with thymoma.
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