Quantitative Relationships between Body Weight, Kidney Weight and Nephron Size in Mongrel Dogs
作者:
M.Q. Zhu,
W. Vaneerdeweg,
N. Buyssens,
M.E. De Broe,
期刊:
Nephron
(Karger Available online 1992)
卷期:
Volume 62,
issue 2
页码: 187-191
ISSN:1660-8151
年代: 1992
DOI:10.1159/000187031
出版商: S. Karger AG
关键词: Nephron size;Morphometry
数据来源: Karger
摘要:
Mammalian species of large stature have larger kidneys with larger nephrons than smaller animals, although this relationship is not linear. In order to investigate whether in animals of different sizes within the same species similar differences exist, a study in mongrel dogs was undertaken. In animals weighing between 9 and 42 kg with kidney weights from 25 to 79 g the area and perimeter of the glomeruli and the cortical width were measured. The number of glomeruli per unit area was counted and corrected for the size of the glomeruli. The results show that larger dogs have larger kidneys and that this enlargement is due to the increase in size of the nephrons and not in their number.
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