Plasma lnterleukin-6 Levels in Continuous Ambulatory Peritoneal Dialysis and Hemodialysis Patients
作者:
Hajime Nakahama,
Yoshimu Tanaka,
Dairoku Shirai,
Mutsuo Miyazaki,
Nobuyuki Imai,
Tomoko Yokokawa,
Mitsunori Okada,
Shujiro Kubori,
期刊:
Nephron
(Karger Available online 1992)
卷期:
Volume 61,
issue 2
页码: 132-134
ISSN:1660-8151
年代: 1992
DOI:10.1159/000186859
出版商: S. Karger AG
关键词: Interleukin-6;Continuous ambulatory peritoneal dialysis;Hemodialysis
数据来源: Karger
摘要:
Plasma levels of interleukin-6 (IL-6), a cytokine known to be involved in lymphocyte activation and in inflammation, were studied in 10 normal volunteers, 21 continuous ambulatory peritoneal dialysis (CAPD) patients and 41 hemodialysis patients. Plasma IL-6 levels in hemodialysis patients were significantly higher than those in normal volunteers and CAPD patients (p < 0.05). The means of plasma IL-6 concentrations before and after hemodialysis did not change significantly. While IL-6 in peritoneal dialysate was detectable in only 3 of the 21 CAPD patients without peritonitis, it was extremely high in 2 patients with bacterial peritonitis. IL-6 levels decreased as peritonitis subsided.
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