Pregnancy and contraception in a French cohort of HIV‐infected women
作者:
Isabelle De Vincenzi,
Corinne Jadand,
Elisabeth Couturier,
Jean-Baptiste Brunet,
Hervé Gallais,
Jean-Albert Gastaut,
Cécile Goujard,
Christiane Deveau,
Laurence Meyer,
期刊:
AIDS
(OVID Available online 1997)
卷期:
Volume 11,
issue 3
页码: 333-338
ISSN:0269-9370
年代: 1997
出版商: OVID
关键词: HIV-infected women;pregnancy outcomes;contraception;France
数据来源: OVID
摘要:
Objective:To describe the impact of HIV diagnosis on contraception, incidence of pregnancy and live-births among HIV-infected women in France.Design:Follow-up of women included in a French cohort of HIV-infected adults (SEROCO).Methods:In 17 hospital-based units and one private practitioners’ network in the Paris area and south-east region of France, 412 HIV-infected women (volunteers) were enrolled from 1988 to 1993, shortly after HIV diagnosis (median, 3 months), and followed for a median of 3 years. The main outcome measures were incidence and outcome of pregnancy, proportions of women sexually active and methods of contraception.Results:The incidence of pregnancy decreased significantly from 20.4 per 100 person-years in the year preceding HIV diagnosis to 7.9 per 100 person-years after HIV diagnosis (P < 0.001), whereas the proportion of pregnancies voluntarily interrupted doubled (63 versus 29%). The proportion of women who were sexually inactive increased from 5% before HIV diagnosis to 20% thereafter. During follow-up, 80% of sexually active women were using contraceptive methods.Conclusions:The study supports an association between the discovery of HIV infection and a decrease in the proportion of women who are sexually active, a decrease in the incidence of pregnancy in general and live-births in particular, and an increase in the proportion of pregnancies voluntarily interrupted. Nevertheless, 24% of the women became pregnant and around 20% of sexually active women were not using any contraception. The high rate of voluntary abortion may indicate that many of these pregnancies were unplanned and could have been prevented.
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