Cerebrospinal Fluid Dynamics in Patients with Pseudotumor Cerebri
作者:
Frederick Sklar,
Chester Beyer,
Murugappan Ramanathan,
Paul Cooper,
Kemp Clark,
期刊:
Neurosurgery
(OVID Available online 1979)
卷期:
Volume 5,
issue 2
页码: 208-216
ISSN:0148-396X
年代: 1979
出版商: OVID
关键词: Cerebral blood flow;Cerebral blood volume;Cerebrospinal fluid;Intracranial pressure;Papilledema;Pseudotumor cerebri
数据来源: OVID
摘要:
&NA;CSF dynamics were determined as a function of intracranial pressure in patients with pseudotumor cerebri. Servocontrolled variable rate lumbar infusions were used to determine net CSF‐absorptive capacities and resting pressures in 10 patients; serial studies were done in 5 of the patients. Nearly all of the patients had abnormally low CSF‐absorptive capacities. On the other hand, marked elevations in resting pressure were not a constant feature of the disease. Concurrent changes in the cerebrovascular bed could introduce errors into this manometric determination of CSF dynamics; the significance of this potential artifact is examined. The results of this study suggest that the CSF compartment may be of etiological importance in the pathophysiology of pseudotumor cerebri.
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